Which medication can cause "red man syndrome" when infused too quickly?

Which medication can cause "red man syndrome" when infused too quickly?

• A. Amphotericin B
• B. Vancomycin
• C. Doxycycline
• D. Ciprofloxacin

Answer: (B)

The correct choice for the medication that can cause "red man syndrome" when infused too quickly is Vancomycin. This syndrome is characterized by flushing, rash, and pruritus, particularly affecting the face and upper body. It results from the rapid release of histamine in response to the medication's infusion, especially when administered too quickly intravenously. It is important to note that while other medications listed have their own specific side effects and infusion considerations, they do not typically evoke the same histamine-mediated reaction associated with red man syndrome. Amphotericin B is more likely to cause nephrotoxicity and infusion-related fever, Doxycycline can cause photosensitivity and gastrointestinal upset, and Ciprofloxacin is associated with various potential side effects including tendon rupture but not red man syndrome. Understanding this specific side effect of Vancomycin is crucial for safe administration practices in clinical settings, ensuring that practitioners infuse it slowly to minimize the risk of adverse reactions.

The correct choice for the medication that can cause "red man syndrome" when infused too quickly is Vancomycin. This syndrome is characterized by flushing, rash, and pruritus, particularly affecting the face and upper body. It results from the rapid release of histamine in response to the medication's infusion, especially when administered too quickly intravenously.

It is important to note that while other medications listed have their own specific side effects and infusion considerations, they do not typically evoke the same histamine-mediated reaction associated with red man syndrome. Amphotericin B is more likely to cause nephrotoxicity and infusion-related fever, Doxycycline can cause photosensitivity and gastrointestinal upset, and Ciprofloxacin is associated with various potential side effects including tendon rupture but not red man syndrome. Understanding this specific side effect of Vancomycin is crucial for safe administration practices in clinical settings, ensuring that practitioners infuse it slowly to minimize the risk of adverse reactions.